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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERCC6L All Species: 14.85
Human Site: S1158 Identified Species: 46.67
UniProt: Q2NKX8 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2NKX8 NP_060139.2 1250 141103 S1158 L S S E N K S S W L M T S K P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001092609 1252 141491 S1162 L S S E N K S S W L T T S K P
Dog Lupus familis XP_549075 1268 143171 S1176 L P S E H K S S W L T T R E P
Cat Felis silvestris
Mouse Mus musculus Q8BHK9 1240 138836 S1149 L A S G N K S S N L T M S E P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505482 1393 155753 E1161 V E E D D Y S E E P A G E T L
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2BGR3 1451 163208 T1360 H S A V L E S T G D V E L D S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P41877 1009 116656 S932 V F E E L R Q S V R M A P Q F
Sea Urchin Strong. purpuratus XP_781405 563 63991 R486 N L R E E K H R C L V F S Q S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.5 78.8 N.A. 73.4 N.A. N.A. 49.9 N.A. N.A. 44.4 N.A. N.A. N.A. 24.7 22.9
Protein Similarity: 100 N.A. 98.4 85.8 N.A. 82.3 N.A. N.A. 63.8 N.A. N.A. 60 N.A. N.A. N.A. 42.7 33.2
P-Site Identity: 100 N.A. 93.3 66.6 N.A. 60 N.A. N.A. 6.6 N.A. N.A. 13.3 N.A. N.A. N.A. 20 26.6
P-Site Similarity: 100 N.A. 93.3 80 N.A. 73.3 N.A. N.A. 26.6 N.A. N.A. 40 N.A. N.A. N.A. 40 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 13 0 0 0 0 0 0 0 13 13 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % C
% Asp: 0 0 0 13 13 0 0 0 0 13 0 0 0 13 0 % D
% Glu: 0 13 25 63 13 13 0 13 13 0 0 13 13 25 0 % E
% Phe: 0 13 0 0 0 0 0 0 0 0 0 13 0 0 13 % F
% Gly: 0 0 0 13 0 0 0 0 13 0 0 13 0 0 0 % G
% His: 13 0 0 0 13 0 13 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 63 0 0 0 0 0 0 0 25 0 % K
% Leu: 50 13 0 0 25 0 0 0 0 63 0 0 13 0 13 % L
% Met: 0 0 0 0 0 0 0 0 0 0 25 13 0 0 0 % M
% Asn: 13 0 0 0 38 0 0 0 13 0 0 0 0 0 0 % N
% Pro: 0 13 0 0 0 0 0 0 0 13 0 0 13 0 50 % P
% Gln: 0 0 0 0 0 0 13 0 0 0 0 0 0 25 0 % Q
% Arg: 0 0 13 0 0 13 0 13 0 13 0 0 13 0 0 % R
% Ser: 0 38 50 0 0 0 75 63 0 0 0 0 50 0 25 % S
% Thr: 0 0 0 0 0 0 0 13 0 0 38 38 0 13 0 % T
% Val: 25 0 0 13 0 0 0 0 13 0 25 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 38 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _